丙甲菌素/阿拉霉素/Alamethicin
Biotech Grade
產品規格 您的價格
1mg 900.00
5mg 2900.00
10mg 5500.00
特殊規格 請詢價
說明：Alamethicin (U-22324) is a polypeptide natural product antibiotic supplied as a mixture of homologs: Alamethicin and Alamethicin I. These compounds form voltage-dependent ion channels in the lipid bilayer, through the spontaneous assembly of units into a multimeric barrel-stave structure spanning the membrane. This formation results in a hydrophilic pore which permits non-specific ion efflux through the membrane. The non-specific ion efflux obliterates the normal electrochemical gradient of the cell, producing the antibiotic property of Alamethicin. Substantiated by experiments with covalently tethered molecules of Alamethicin, It is suggested that different multimeric aggregation states create varying pore sizes with varying stabilities, correlating to differential specificity for ions. This channel-forming activity has been exploited as a tool for introducing hydrophilic small molecules into mitochondria without disrupting the integrity of the membrane.
CAS：27061-78-5
分子式：C92H150N22O25
分子量：1964.31
純度：98%
保存： 2-8℃
From RuiTaibio
本產品由北京中成謹念/中生瑞泰科技有限公司優惠供應，公司常年現貨，歡迎廣大科研工作者及經銷商同仁前來咨詢選購；另外公司專業從事進口科研生化試劑的批發及零售業務，產品涉及分子生物學、細胞生物學、免疫學、生物化學等諸多生命科研領域。因公司業務發展的需要，現誠征各地經銷代理商，歡迎有志從事本行業的精英、同行蒞臨指導。
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